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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA unwinding involved in DNA replication
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Accession:GO:0006268 term browser browse the term
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Comment:Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Synonyms:related_synonym: DNA unwinding during replication;   DNA unwinding factor

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DNA unwinding involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254 		JBrowse link
G CDC45 cell division cycle 45 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr19:6,232,610...6,275,743
Ensembl chr19:6,231,591...6,275,294 		JBrowse link
G GINS2 GINS complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,088,766...71,099,845
Ensembl chr 5:71,089,564...71,099,688 		JBrowse link
G GINS3 GINS complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,331,392...44,342,754
Ensembl chr 5:44,331,802...44,342,812 		JBrowse link
G GINS4 GINS complex subunit 4 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr 8:39,509,833...39,523,099
Ensembl chr 8:39,509,847...39,526,321 		JBrowse link
G LOC103216161 uncharacterized LOC103216161 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr 2:56,448,443...56,467,908
Ensembl chr 2:56,448,392...56,467,712 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10531422) Ensembl
MGI
TreeGrafter		 PMID:10531422 GO_REF:0000107 GO_REF:0000118 NCBI chr22:53,419,958...53,452,720
Ensembl chr22:53,420,417...53,444,095 		JBrowse link
G MCM3 minichromosome maintenance complex component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,222,440...20,243,807
Ensembl chr17:20,222,590...20,243,809 		JBrowse link
G MCM4 minichromosome maintenance complex component 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) Ensembl
MGI
TreeGrafter		 PMID:15917436 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:44,120,291...44,136,625
Ensembl chr 8:44,120,301...44,138,193 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 involved_in ISO (PMID:22474384) ComplexPortal PMID:22474384 NCBI chr19:18,164,743...18,189,223
Ensembl chr19:18,164,879...18,189,284 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) Ensembl
MGI
TreeGrafter		 PMID:15917436 GO_REF:0000107 GO_REF:0000118 NCBI chr10:20,053,726...20,089,571
Ensembl chr10:20,051,138...20,089,545 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917436) TreeGrafter
MGI		 PMID:15917436 GO_REF:0000118 NCBI chr28:12,976,487...12,985,354
Ensembl chr28:12,977,013...12,985,898 		JBrowse link
G PURA purine rich element binding protein A involved_in ISO (PMID:15777841) UniProt PMID:15777841 NCBI chr23:42,757,963...42,767,393
Ensembl chr23:42,764,263...42,765,231 		JBrowse link
G RAD51 RAD51 recombinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169 		JBrowse link
G RECQL RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:21,334,601...21,366,943
Ensembl chr11:21,331,584...21,366,979 		JBrowse link
G RECQL4 RecQ like helicase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:138,725,494...138,732,286
Ensembl chr 8:138,725,633...138,732,096 		JBrowse link
G RECQL5 RecQ like helicase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:46,013,100...46,052,713
Ensembl chr16:46,013,092...46,056,167 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
G TWNK twinkle mtDNA helicase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11431692) Ensembl
MGI		 PMID:11431692 GO_REF:0000107 NCBI chr 9:94,006,183...94,012,783
Ensembl chr 9:94,006,188...94,013,164 		JBrowse link
G WRN WRN RecQ like helicase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:29,150,256...29,288,830
Ensembl chr 8:29,174,229...29,289,129 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    metabolic process 10515
      organic substance metabolic process 10067
        macromolecule metabolic process 8484
          nucleic acid metabolic process 4699
            DNA metabolic process 906
              DNA replication 264
                DNA-templated DNA replication 158
                  DNA unwinding involved in DNA replication 20
                    cell cycle DNA replication DNA unwinding + 0
Path 2
Term Annotations click to browse term
  biological_process 16925
    metabolic process 10515
      organic substance metabolic process 10067
        organic cyclic compound metabolic process 5666
          nucleobase-containing compound metabolic process 5211
            nucleic acid metabolic process 4699
              DNA metabolic process 906
                DNA replication 264
                  DNA-templated DNA replication 158
                    DNA unwinding involved in DNA replication 20
                      cell cycle DNA replication DNA unwinding + 0
paths to the root